Asymmetry in Parkinson’s Disease: Exploring the Role of Hemispheric Specialization in Treatment Success

Authors

  • Dipesh Pokharel The University of Toledo College of Medicine and Life Science, Department of Neurosciences/Neurology Author https://orcid.org/0000-0002-3593-3367
    • Caroline Swain The University of Toledo College of Medicine and Life Science Department of Neurosciences/Neurology Author
      • Dilshan Beligala Department of Neurology, The university of Toledo Author https://orcid.org/0000-0002-3760-4479
        • Isable Nester Department of Neurology, The University of Toledo Author https://orcid.org/0009-0009-9141-974X
          • Khoi Le Department of Neurology, The University of Toledo Author
            • Vaibhavi Peshattiwar Department of Neurology, The University of Toledo Author
              • Kala Venkiteswaran Department of Neurology/Neurosciences, The University of Toledo Author
                • Thyagarajan Subramanian Department of Neurosciences,Neurology and Bioengineering, The University of Toledo Author

                  DOI:

                  https://doi.org/10.46570/utjms-2025-1475

                  Keywords:

                  Limb Dominance, Hemisperic dominance, Hemispheric lateralization, Parkinson's Disease, Hemispheric specialization, Handedness, Pawedness
                  445 257

                  References

                  Li, P., Ensink, E., Lang, S., Marshall, L., Schilthuis, M., Lamp, J., Vega, I., & Labrie, V. (2020). Hemispheric asymmetry in the human brain and in Parkinson's disease is linked to divergent epigenetic patterns in neurons. Genome biology, 21(1), 61. https://doi.org/10.1186/s13059-020-01960-1 DOI: https://doi.org/10.1186/s13059-020-01960-1

                  Pagano, G., Ferrara, N., Brooks, D. J., & Pavese, N. (2016). Age at onset and Parkinson's disease phenotype. Neurology, 86(15), 1400–1407. https://doi.org/10.1212/WNL.0000000000002461 DOI: https://doi.org/10.1212/WNL.0000000000002461

                  Wang, J., Yang, Q. X., Sun, X., Vesek, J., Mosher, Z., Vasavada, M., Chu, J., Kanekar, S., Shivkumar, V., Venkiteswaran, K., & Subramanian, T. (2015). MRI evaluation of asymmetry of nigrostriatal damage in the early stage of early-onset Parkinson's disease. Parkinsonism & related disorders, 21(6), 590–596. https://doi.org/10.1016/j.parkreldis.2015.03.012 DOI: https://doi.org/10.1016/j.parkreldis.2015.03.012

                  Pençe S. (2002). Paw preference in rats. Journal of basic and clinical physiology and pharmacology, 13(1), 41–49. https://doi.org/10.1515/jbcpp.2002.13.1.41 DOI: https://doi.org/10.1515/JBCPP.2002.13.1.41

                  Nikkhah, G., Falkenstein, G., & Rosenthal, C. (2001). Restorative plasticity of dopamine neuronal transplants depends on the degree of hemispheric dominance. The Journal of neuroscience: the official journal of the Society for Neuroscience, 21(16), 6252–6263. https://doi.org/10.1523/JNEUROSCI.21-16-06252.2001 DOI: https://doi.org/10.1523/JNEUROSCI.21-16-06252.2001

                  Downloads

                  Published

                  2025-10-15

                  Issue

                  Section

                  Departments of Neuroscience and Psychiatry Research Symposium

                  How to Cite

                  1.
                  Pokharel D, Swain C, Beligala D, et al. Asymmetry in Parkinson’s Disease: Exploring the Role of Hemispheric Specialization in Treatment Success. Translation. 2025;14(S1). doi:10.46570/utjms-2025-1475

                  Similar Articles

                  31-40 of 87

                  You may also start an advanced similarity search for this article.

                  Most read articles by the same author(s)