Asymmetry in Parkinson’s Disease: Exploring the Role of Hemispheric Specialization in Treatment Success

Authors

  • Dipesh Pokharel The University of Toledo College of Medicine and Life Science, Department of Neurosciences/Neurology Author https://orcid.org/0000-0002-3593-3367
  • Caroline Swain The University of Toledo College of Medicine and Life Science Department of Neurosciences/Neurology Author
  • Dilshan Beligala Department of Neurology, The university of Toledo Author https://orcid.org/0000-0002-3760-4479
  • Isable Nester Department of Neurology, The University of Toledo Author https://orcid.org/0009-0009-9141-974X
  • Khoi Le Department of Neurology, The University of Toledo Author
  • Vaibhavi Peshattiwar Department of Neurology, The University of Toledo Author
  • Kala Venkiteswaran Department of Neurology/Neurosciences, The University of Toledo Author
  • Thyagarajan Subramanian Department of Neurosciences,Neurology and Bioengineering, The University of Toledo Author

DOI:

https://doi.org/10.46570/utjms-2025-1475

Keywords:

Limb Dominance, Hemisperic dominance, Hemispheric lateralization, Parkinson's Disease, Hemispheric specialization, Handedness, Pawedness

References

Li, P., Ensink, E., Lang, S., Marshall, L., Schilthuis, M., Lamp, J., Vega, I., & Labrie, V. (2020). Hemispheric asymmetry in the human brain and in Parkinson's disease is linked to divergent epigenetic patterns in neurons. Genome biology, 21(1), 61. https://doi.org/10.1186/s13059-020-01960-1

Pagano, G., Ferrara, N., Brooks, D. J., & Pavese, N. (2016). Age at onset and Parkinson's disease phenotype. Neurology, 86(15), 1400–1407. https://doi.org/10.1212/WNL.0000000000002461

Wang, J., Yang, Q. X., Sun, X., Vesek, J., Mosher, Z., Vasavada, M., Chu, J., Kanekar, S., Shivkumar, V., Venkiteswaran, K., & Subramanian, T. (2015). MRI evaluation of asymmetry of nigrostriatal damage in the early stage of early-onset Parkinson's disease. Parkinsonism & related disorders, 21(6), 590–596. https://doi.org/10.1016/j.parkreldis.2015.03.012

Pençe S. (2002). Paw preference in rats. Journal of basic and clinical physiology and pharmacology, 13(1), 41–49. https://doi.org/10.1515/jbcpp.2002.13.1.41

Nikkhah, G., Falkenstein, G., & Rosenthal, C. (2001). Restorative plasticity of dopamine neuronal transplants depends on the degree of hemispheric dominance. The Journal of neuroscience: the official journal of the Society for Neuroscience, 21(16), 6252–6263. https://doi.org/10.1523/JNEUROSCI.21-16-06252.2001

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Published

2025-10-15

Issue

Vol. 14 No. S1 (2025): 2025 Department of Neurosciences and Psychiatry Symposium

Section

Departments of Neuroscience and Psychiatry Research Symposium

License

Copyright (c) 2025 Dipesh Pokharel, Caroline Swain , Dilshan Beligala, Isable Nester , Khoi Le , Vaibhavi Peshattiwar, Kala Venkiteswaran , Thyagarajan Subramanian (Author)

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How to Cite

1.
Asymmetry in Parkinson’s Disease: Exploring the Role of Hemispheric Specialization in Treatment Success. Translation. 2025;14(S1). doi:10.46570/utjms-2025-1475

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